That 5-2 victory has made the Owls’ next opponents, Derby County, sit up and take notice.
The Rams will face Wednesday at home on Saturday hoping that they can bounce back from a 2-1 defeat at QPR and that the Owls’ thrashing of Reading is not the start of a big revival for them.
Coach Paul Simpson said: ““We are all disappointed to have lost at the weekend but the Championship is a crazy league.
“I don’t think anybody thought Nottingham Forest would lose at home (1-0 to Blackpool) or would have predicted Sheffield Wednesday’s first win would be by a 5-2 scoreline.
“We know it is going to be a tough game.”
It was Derby’s first defeat in five games and the first since Steve McClaren took charge of the team.
Simpson also says: “It is important not to get down after a defeat..
“We are delighted with the start we have had, the attitude of the players and the positive feeling we are getting from the supporters.
“So we are not going to get down, just as we didn’t get carried away when we beat Watford or Leeds.
“Maybe we needed a little bit of a check. It just keeps everybody’s feet on the ground.
“It would have been nice to come away from QPR with something and take us into the weekend unbeaten but we didn’t and so we start again and hopefully go on another run.”
McClaren was hired after a 1-0 defeat against Forest spelled the axe for Nigel Clough.
Former England boss McClaren watched a 4-4 home draw with Ipswich then took took full charge for victories at home to Leeds, 3-1, and away against Watford, 3-2.
Wednesday too lost 2-1 at QPR, on the opening day of the season, but at that early stage they did not have the sort of firepower seen last Saturday from loan arrivals Connor Wickham and Matty Fryatt.
Wickham got off the mark against Reading; Fryatt moved on a four-goal total.
While the Owls’ preparations are running smoothly for the Derby game, McClaren must decide on a replacement for the experienced John Eustace.
He collected his fifth booking of the season at QPR so is suspended for one game.
Dave Jones kept Jacques Maghoma ticking by giving him 80 minutes of the Under 21s’ 3-3 draw with Crewe.
The left winger scored the third goal and hit the post before a late equaliser. The Owls led 1-0 and 2-1 thanks to Caolan Lavery, who netted a penalty and a goal from a flick by Robbie Simpson.
There were chances for both sides and saves from both keepers but Wednesday largely had the edge.
Team: Dawson, Harvey, Obileye, McKenzie, Floro, Savic (Lambin 63), Corry, McCabe, Maghoma (Betra 80), Simpson, Lavery. Unused subs: Hinchliffe, Wildsmith, Fenwick.
The Under 21s play Leicester away in the league cup on November 19.