Stocksbridge Park Steels bid farewell to the Premier Division against Skemersdale United at Bracken Moor following a five-year stay in the NPL top flight.
After ending a run of 14 defeats on the spin with two draws over the Easter weekend, relegated Steels will look to bow out with a first win in 23 games in what could be manager Darren Schofield last game in charge.
The Steels boss said: “We’ll sit down at the end of the season and have a chat about how we are going to move forward and what is the best for the club. Either way, I don’t want another season of struggle so there are things like finances to sort out and what budget will be available in order make the changes that are needed to the squad.
“It’s something I expect will be sorted out quickly.”
Leading scorer Nathan Joynes is almost certain to miss out with an ankle injury, while central defender Richard Haigh is rated very doubtful. But striker Jamie Smith should have recovered from a slight hamstring and Chris Hamilton should be fit.
Elsewhere, Sheffield FC sign off their season with a trip to bottom of the table Kidsgrove Athletic who have lost nine and won two of their last 11 games.
Club, who drew 1-1 with Scarborough Athletic on Wednesday evening in their last home game, will be hoping to end a run of four successive away defeats.
Fourth-placed Worksop Town, who have already booked their place in the play-offs which get underway next week, are unbeaten in three outings and host Frickley Athletic, who were relegated following a 2-2 draw against Stocksbridge on Monday.