Photos show how five fire engines were needed to fight the blaze at the corner of Campo Lane and North Church Street starting at around 10pm.
The buildings at the junction are a mix of offices, flats and a number of shops, including a juice bar and a barbers. It is unclear at this time which buildings have been affected directly or if anyone was injured in the incident.
A resident nearby told The Star how they feared the blaze spreading to their homes, and how they had to shut their windows to keep smopke out.
The street was shut well into the early hours of October 8 while officers dealt with the blaze.
South Yorkshire Fire & Rescue has been contacted for a comment.
1. Fire on North Church Street
The buildings at the junction on North Church Street and Campo Lane are a mix of shops, offices and flats. South Yorkshire Fire & rescue are yet to say which buildings have been directly affected.
2. Mix of shops, offices and flats
The buildings at the junction on North Church Street and Campo Lane are a mix of shops, offices and flats. South Yorkshire Fire & rescue are yet to say which buildings have been directly affected.
3. Fire on North Church Street
Five fire appliances were called to the building at the junction of Campo Lane and North Church Street where a severe fire had broken out in a mixed-use building.
4. Major fire
Residents in the area told The Star how they feared the blaze spreading to other buildings, and that they had to close their windows to keep smoke out their homes.